WP2: Fabrication and Characterization of Si NW FETs Array
The overreaching goal of this WP is to develop arrays of chemically-sensitive field effect transistors (FETs) of molecule-terminated silicon nanowires (Si NWs) and to test the feasibility of the developed devices for sensing volatile biomarkers of LC from in-vitro tissues and from human exhaled breath. More specifically, the objectives of WP2 will be:
- Having a set of fully functionalized Si NWs.
- Achieving a set of highly-efficient fabrication processes for Si NW FET devices.
- Determining the most informative device parameters.
- Determining the relationship between (i) the electrical and/or sensing parameters and (ii) sensor specifics.
- Having a set of pattern recognition models which have been successfully used to analyze the output signals of the sensor array.
- Understanding of the signal transduction mechanism of the various volatile biomarkers and metabolites.
- Testing SiNW FETs array, with proven ability to sense volatile biomarkers of pre- and post-cancerous conditions, from in-vitro tissues and from exhaled human breath.
- Testing the performance of the Si NW FETs after integration in a microfludic cell.
- Testing the performance of the Si NW FETs after integration in a stand-alone ‘NA-NOSE’.